Antibacterial protein

Details Antibacterial protein Antibacterial protein

1998-01-28

2000-05-16

Davenport, Avis M.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

530300, 530350, 424404, A61K 3800, C07K 100, C07K 500, A10N 2534

Patent

active

06063765&

ABSTRACT:
The present invention relates to a novel antibacterial protein, called gloverin. Preferably, gloverin is isolated from Hyalophora moths. Alternatively, gloverin is produced by genetic engineering or by chemical synthesis.
Also, the invention relates to pharmaceutical compositions comprising gloverin or pharmaceutically active fragments thereof and use of gloverin or fragments thereof as a medicament against bacterial infection. Furthermore, the invention relates to a method of treating bacterial infection comprising administration of gloverin or pharmaceutically active fragments thereof.

REFERENCES:
Spies, Karlinsey and Spence, "Antibacterial Hemolymph Proteins Of Manduca Sexta", Comp. Biochem. Physiol, vol. 83B, No. 1, pp. 125-133, 1986 Great Britain.
Axen et al., Eur. J. Biochem, vol. 247, pp. 614-619, 1997.

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