Drug – bio-affecting and body treating compositions – Dentifrices – Fluorine or fluorine compound containing
Patent
1977-06-03
1979-01-30
Rose, Shep K.
Drug, bio-affecting and body treating compositions
Dentifrices
Fluorine or fluorine compound containing
424 54, A61K 716, A61K 718, A61K 722
Patent
active
041373030
ABSTRACT:
An antibacterial oral composition effective to promote oral hygiene containing an antibacterial antiplaque agent and an additive which reduces staining of dental surfaces caused by the antibacterial antiplaque agent without substantially diminishing the antibacterial and antiplaque activity of the agent. Bis-biguanido hexanes, such as chlorhexidine and alexidine, and quaternary ammonium salts, such as benzethonium chloride and cetyl pyridinium chloride, are typical examples of antibacterial agents. The stain reduction additive is a polyamine polyphosphonic compound, such as ethylenediamine tetra(methylene phosphonic acid) and salts thereof.
REFERENCES:
patent: 3934002 (1976-01-01), Haefele
Chem. Abstracts 80 #30710a(1974) of Crutchfield et al. Fr. Demande 2,159,507 27 Jul. 1973, 12 pp., "Tartar-Retarding Toothpastes Containing Polyamine Polyphosphonates".
Chem. Abstracts 84 #111684e(1976) of Haefele U.S. 3,934,002 20 Jan. 1976, "Oral Compositions for Plaque Caries and Calculus Retardation with Reduced Staining Tendencies".
Gaffar Abdul
Volpe Anthony R.
Colgate - Palmolive Company
Grill Murray M.
Rose Shep K.
Stone Robert L.
Sylvester Herbert S.
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