Drug – bio-affecting and body treating compositions – Dentifrices – Ammonia – amine – or derivative thereof
Patent
1979-08-24
1980-09-23
Rose, Shep K.
Drug, bio-affecting and body treating compositions
Dentifrices
Ammonia, amine, or derivative thereof
424 49, A61K 722, A61K 716
Patent
active
042243092
ABSTRACT:
An antibacterial oral composition effective to promote oral hygiene containing an antibacterial antiplaque agent which normally stains dental surfaces and an additive which reduces such staining without substantially diminishing the antibacterial and antiplaque activity of the agent. Bis-biguanido hexanes, such as chlorohexidine and alexidine, and quaternary ammonium salts, such as benzethonium chloride and cetyl pyridinium chloride are typical examples of antibacterial agents. The antistain additive is 2-phosphono-butane-1,2,4-tricarboxylic acid compound or an orally acceptable salt thereof.
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Gaffar Abdul
Grecsek John J.
Blumenkopf Norman
Colgate-Palmolive Company
Grill Murray M.
Rose Shep K.
Sylvester Herbert S.
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