Drug – bio-affecting and body treating compositions – Dentifrices – Ammonia – amine – or derivative thereof
Patent
1977-04-25
1978-10-31
Rose, Shep K.
Drug, bio-affecting and body treating compositions
Dentifrices
Ammonia, amine, or derivative thereof
424 52, 424 57, A61K 716, A61K 722
Patent
active
041235126
ABSTRACT:
An antibacterial oral composition effective to promote oral hygiene containing an antibacterial antiplaque agent and an additive which reduces staining of dental surfaces without substantially diminishing the antibacterial and antiplaque activity of the agent. Bis-biguanido hexanes, such as chlorhexidine and alexidine, and quaternary ammonium salts, such as benzethonium chloride and cetyl pyridinium chloride, are typical examples of antibacterial agents. The antistain additive is a polymeric polyphosphonic compound, such as polyallyl bis-(phosphonomethylene) amine acid and salts thereof.
REFERENCES:
patent: 3429963 (1969-02-01), Shedlovsky
patent: 3934002 (1976-01-01), Haefele
patent: 3937805 (1976-02-01), Harrison
patent: 3956480 (1976-05-01), Dichter et al.
patent: 3959458 (1976-05-01), Agricola et al.
patent: 4025616 (1977-05-01), Haefele
patent: 4042679 (1977-08-01), Gaffar
Chem. Abstracts 77 #66118r (1972) of Ger. Offen. 2, 156,491 May 31, 1972, "Sodium Polyethylene Polyphosphonates for Dentifrices".
Chem. Abstracts 80 #30710a (1974) of Fr. Demande 2,159,507, Jul. 27, 1973, "Tartar-Retarding Toothpastes Containing Polyamine Polyphosphonates".
Chem. Abstracts 85 #130545x (1976) of Fr. Demande 2,280,362, Feb. 27, 1976, "Tartar-Retarding Toothpastes Containing Polyamine Polyphosphonates".
Anbar et al., Chem. Abstracts 82 #164761t (1975), 82 #25739d (1975), 82 #35008d (1975), "Organic Polymeric Polyphosphonates as Potential Preventive Agents of Dental Caries".
Colgate-Palmolive Company
Grill Murray M.
Rose Shep K.
Stone Robert L.
Sylvester Herbert S.
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