Antibacterial oral composition

Drug – bio-affecting and body treating compositions – Dentifrices – Ammonia – amine – or derivative thereof

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424 57, 424 49, A61K 722, A61K 716

Patent

active

041184734

ABSTRACT:
An antibacterial oral composition effective to promote oral hygiene containing an antibacterial antiplaque agent and an additive which reduces staining of dental surfaces without substantially diminishing the antibacterial and antiplaque activity of the agent. Bis-biguanido hexanes, such as chlorhexidine and alexidine, and quaternary ammonium salts, such as benzethonium chloride and cetyl pyridinium chloride, are typical examples of antibacterial agents. The antistain additive is an N-methylene phosphonate compound, such as iminodiacetic N-methylene phosphonic acid and salts thereof.

REFERENCES:
patent: 3325402 (1967-06-01), Mortimer
patent: 3431208 (1969-03-01), Bailey
patent: 3925456 (1975-12-01), Ploger et al.
patent: 3941772 (1976-03-01), Ploger et al.
patent: 4042679 (1977-08-01), Gaffar
Hargreaves et al., "Antimicrobal . . . products Chem. Abstracts", vol. 82, 1975, p. 15 3831q.

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