Drug – bio-affecting and body treating compositions – Dentifrices – Ammonia – amine – or derivative thereof
Patent
1976-08-16
1978-10-03
Jiles, Henry R.
Drug, bio-affecting and body treating compositions
Dentifrices
Ammonia, amine, or derivative thereof
424 57, 424 49, A61K 722, A61K 716
Patent
active
041184734
ABSTRACT:
An antibacterial oral composition effective to promote oral hygiene containing an antibacterial antiplaque agent and an additive which reduces staining of dental surfaces without substantially diminishing the antibacterial and antiplaque activity of the agent. Bis-biguanido hexanes, such as chlorhexidine and alexidine, and quaternary ammonium salts, such as benzethonium chloride and cetyl pyridinium chloride, are typical examples of antibacterial agents. The antistain additive is an N-methylene phosphonate compound, such as iminodiacetic N-methylene phosphonic acid and salts thereof.
REFERENCES:
patent: 3325402 (1967-06-01), Mortimer
patent: 3431208 (1969-03-01), Bailey
patent: 3925456 (1975-12-01), Ploger et al.
patent: 3941772 (1976-03-01), Ploger et al.
patent: 4042679 (1977-08-01), Gaffar
Hargreaves et al., "Antimicrobal . . . products Chem. Abstracts", vol. 82, 1975, p. 15 3831q.
Gaffar Abdul
Niles Hollandra P.
Colgate-Palmolive Company
Grill Murray M.
Jiles Henry R.
Owens Cary
Stone Robert L.
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