Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1986-12-12
1989-06-13
Rizzo, Nicholas S.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
540227, 540225, 514203, C07D50136, A61K 31545
Patent
active
048393517
ABSTRACT:
A compound of the general formula: ##STR1## wherein R.sup.0 is hydrogen, a nitrogen-containing heterocyclic group, an acyl group or an amino-protective group; A is S, S.fwdarw.O, O or CH.sub.2 ; R.sup.4 is hydrogen, methoxy group or formamido group; R.sup.13 is hydrogen, methyl, hydroxyl or a halogen; and A is an optionally substituted condensed cyclic group formed by combining an imidazole or pyrazole ring with 5- or 6-membered nitrogen-containing aromatic heterocyclic ring to share a C-N bond with each other,
or a salt or ester thereof.
and a process for preparing the same and a pharmaceutical composition thereof are disclosed.
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Hashimoto Naoto
Miyake Akio
Nishimura Tatsuo
Yoshimura Yoshinobu
Rizzo Nicholas S.
Takeda Chemical Industries Ltd.
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