Antibacterial compositions

Details Antibacterial compositions Antibacterial compositions

1995-10-18

1997-10-21

Fay, Zohreh

Drug, bio-affecting and body treating compositions

Topical body preparation containing solid synthetic organic...

Ophthalmic preparation

514254, 514912, A61K 3174

Patent

active

056793367

ABSTRACT:
Aqueous pharmaceutical compositions containing a synergistic combination of a quinolone and a polystyrene sulfonic acid polymer are described, wherein the compositions are clear solutions which are comfortable and have sustained release. Methods for use of the compositions are also disclosed. This type of formulation is particularly useful with ciprofloxacin-type quinolones by greatly increasing the solubility of these quinolones, making it feasible to have aqueous solutions containing such quinolones at or near physiological pH.

REFERENCES:
patent: 4146719 (1979-03-01), Irikura
patent: 4292317 (1981-09-01), Pesson
patent: 4382892 (1983-05-01), Hayakawa et al.
patent: 4615882 (1986-10-01), Stockel
patent: 4670444 (1987-06-01), Grohe et al.

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