Antibacterial benzo(chalcogeno)[4,3,2-cd]indazoles

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

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514227, 514231, 514234, 514237, 514239, 514255, 514376, 544 587, 544 60, 544137, 544140, 544369, 544371, 548229, 548370, A61K 31415, A61K 3154, C07D49106, C07D51706

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active

046043900

ABSTRACT:
Substituted 2H-[1]benzopyrano[4,3,2-cd]indazoles, 2H-[1]benzothiopyrano[4,3,2-cd]indazoles, and 2H-[1]benzoselenino[4,3,2-cd]indazoles have demonstrated pharmacological activity against a broad spectrum of Gram-positive and Gram-negative bacteria, yeasts, and fungi, as well as activity against the L1210 and P388 murine leukemia cells lines.
Pharmaceutical compositions containing the compounds and methods of employing the compounds in methods of treating bacterial or fungal infections and of inhibiting the growth of neoplasms in mammals are also disclosed.

REFERENCES:
patent: 3505341 (1970-04-01), Elslager et al.
patent: 3816438 (1974-06-01), Houlihan
patent: 3963740 (1976-06-01), Elslager

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