Antibacterial, antiplaque, anticalculus oral composition

Details Antibacterial, antiplaque, anticalculus oral composition Antibacterial, antiplaque, anticalculus oral composition

1989-05-01

1991-08-27

Griffin, Ronald W.

Drug, bio-affecting and body treating compositions

Dentifrices

Fluorine or fluorine compound containing

424 49, 424 54, 424 57, 514835, 514902, A61K 718, A61K 716

Patent

active

050431544

ABSTRACT:
An oral composition such as a dentifrice, mouthwash, lozenge or chewing gum containing a polyphosphate anticalculus agent, such as tetraalkali metal pyrophosphate and antibacterial antiplaque agent compatible therewith. The antiplaque agent is a substantially water-insoluble noncationic antibacterial agent such as 2,4,4'-trichloro-2.sup.1 -hydroxydiphenyl ether (Triclosan).

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The Effects of a Dentifrice Containing Zinc Citrate and 2,4,4', Trichloro-2'-Hydroxydiphenyl Ether, Saxton, J. Periodont., Sep. 1986, vol. 57, No. 9, pp. 555-561.
Oral Disposition of Triclosan Delivered from a Dentifrice, Caries Research, 1987, vol. 21, pp. 29-36, Gilbert et al., (published on or about Jan. 21, 1987).

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