Antibacterial and fungicidal agent

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514400, 514655, A01N 3304, A01N 4330, A01N 4350

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active

057863865

ABSTRACT:
The present invention provides an antibacterial and fungicidal agent containing an amino compound of formula (1) or a salt thereof. The invention also provides a method for imparting antibacterial and fungicidal properties to a variety of objects using the compound. ##STR1## wherein .phi. represents a phenyl group, a substituted phenyl group (wherein the substituents are 1-5 members arbitrarily selected from the group consisting of a hydroxyl group, halogen atoms, lower alkoxyl groups, trifluoromethyl group, an amino group, and a methylenedioxy group), or an imidazolyl group; R.sup.1 represents a hydrogen atom or a lower alkyl group; and R.sup.2 represents a C6-C12 alkyl group. The amino compound of formula (1) or a salt thereof exhibits excellent antibacterial effects and fungicidal effects, and when it is applied to a variety of articles used in industry, commodities, etc., enhanced antibacterial effects and fungicidal effects are obtained.

REFERENCES:
patent: 4372969 (1983-02-01), Lafon
Biochemical Pharmacology, vol. 30, No. 22, pp. 3045-3049, 1981, Robin J. Breckenridge, et al., "Inhibition of Neuronal GABA Uptake and Glial .beta.-Alanine Uptake by Synthetic GABA Analogues".
Biochemical Pharmacology, vol. 34, No. 23, pp. 4173-4177, 1985, "Non-Selective Inhibition of GABA and 5-HT Uptake Systems in Rat Brain by N-n-Alkyl Hydroxybenzylamine and N-n-alkyl Phenylethylamine Derivatives".
J. Med. Chem., vol. 36, No. 9, pp. 1262-1271, 1993, Melvin J. Yu, et al., "Benzylamine Antioxidants: Relationship Between Structure, Peroxyl Radical Scavenging, Lipid Peroxidation Inhibition, and Cytoprotection".
Journal of Neurochemistry, vol. 37, No. 4, pp. 837-844, 1981, Robin J. Postsynaptic Receptors in Human Cerebellar Synaptic Membranes by Carboxyl and Amino Derivatives of GABA ".

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