Antibacterial and antiprotozoal 1-methyl-5-nitro-2-(2-phenylviny

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...

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424272, 424273R, 542405, A01N 4350, A01N 4384, C07D23394, C07D41310

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active

044230460

ABSTRACT:
1-Methyl-5-nitro-2-(2-phenylvinyl)imidazoles, having useful antibacterial and antiprotozoal activities, are prepared by chemical transformations of the cyano functional group in a corresponding 1-methyl-5-nitro-2-[2-(cyanophenyl)vinyl]imidazole.

REFERENCES:
patent: 3391156 (1968-07-01), Beaman et al.
patent: 3487087 (1969-12-01), Sarett et al.
patent: 3549626 (1970-12-01), Miller et al.
patent: 3658797 (1972-04-01), Ross et al.
Ross et al., J. Med. Chem. 15, 1035-1040 (1972).
Ross et al., J. Med. Chem. 16, 347 (1973).

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