Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...
Patent
1981-11-13
1983-02-15
Trousof, Natalie
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Bacterium or component thereof or substance produced by said...
2602391, 546156, A61K 3147, C07D49970, C07D21522
Patent
active
043741380
ABSTRACT:
Novel organic amide compounds which are N-[ureidodihydro-oxo-3-quinolinylcarbonyl]penicillin compounds having broad spectrum antibacterial utility are provided by (a) reacting the free amino acid of the appropriate penicillin or the acid salt or silylated derivative or complex thereof with a reactive derivative of the corresponding ureido-dihydro-oxo-3-quinolinecarboxylic acid or (b) reacting the free amino acid 6-aminopenicillanic acid or a related compound or the acid salt or silylated derivative thereof with a reactive derivative of the corresponding D-N-[ureidodihydro-oxo-3-quinolinylcarbonyl]-2-substituted glycine. Pharmaceutical compositions containing said compounds and methods for treating infections using said compositions are also disclosed.
REFERENCES:
patent: 4241062 (1980-12-01), Hannah
patent: 4263302 (1981-04-01), Matsubara et al.
patent: 4273932 (1981-06-01), Matsubara et al.
Haskell Theodore H.
Hutt Marland P.
Clarke Vera C.
Patton Walter
Trousof Natalie
Warner-Lambert & Company
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