Drug – bio-affecting and body treating compositions – Conjugate or complex of monoclonal or polyclonal antibody,... – Conjugated via claimed linking group – bond – chelating agent,...
Patent
1979-06-11
1981-02-10
Brown, Johnnie R.
Drug, bio-affecting and body treating compositions
Conjugate or complex of monoclonal or polyclonal antibody,...
Conjugated via claimed linking group, bond, chelating agent,...
536 1, 536 17R, 435 80, A61K 3171, C07H 1522
Patent
active
042501709
ABSTRACT:
A novel water-soluble basic antibiotic complex designated herein as Bu-2349 is produced by fermentation of Bu-2349-producing strains of the genus Bacillus. Complex Bu-2349 and its bioactive components designated as Bu-2349A and B are found to possess marked inhibitory activity against gram-positive and gram-negative bacteria including various types of aminoglycoside-resistant bacteria.
REFERENCES:
patent: 4007167 (1977-02-01), Martin et al.
patent: 4048431 (1977-09-01), Hlavka et al.
patent: 4066753 (1978-01-01), Hanesslan
patent: 4123607 (1978-10-01), Hlavka et al.
Kawaguchi Hiroshi
Konishi Masataka
Miyaki Takeo
Tsuno Takashi
Bristol-Myers Company
Brown Johnnie R.
Morse David M.
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