Antibacterial agents

Details Antibacterial agents Antibacterial agents

2005-03-08

2005-03-08

Rao, Deepak (Department: 1624)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

C514S255050, C514S259400, C514S259410, C514S228200, C514S233200, C544S282000, C544S061000, C544S116000, C544S119000

Reexamination Certificate

active

06864259

ABSTRACT:
The present invention provides compounds of Formula (I):wherein R1-R6and K have any of the values defined in the specification, and pharmaceutically acceptable salt thereof, that are useful as antibacterial agents. Also disclosed are pharmaceutical compositions comprising one or more compounds of Formula I, processes for preparing compounds of Formula I, and intermediates useful for preparing compounds of Formula I.

REFERENCES:
patent: 35619 (1981-09-01), None
patent: 2097784 (1982-11-01), None
patent: WO 9414809 (1994-07-01), None
patent: WO 9422449 (1994-10-01), None
patent: WO 9510519 (1995-04-01), None
patent: WO 9818781 (1998-05-01), None
patent: WO 9921840 (1999-05-01), None
patent: WO 9961444 (1999-12-01), None
patent: WO 0153273 (2001-07-01), None
Hunger et al., CAPLUS Abstract 52:50662, 1958.*
Garcia-Quintana, H.G., et al., Study of benzotriazepines and quinazolines obtained by synthesis on bacterial populations, J. Vet. Med., Series B, vol. 34(5): 341-346 (1987).
Kornet, M.J., et al., Synthesis of 3-amino-2-4 (1H, 3H)-quinazolinediones for testing as anticonvulsants, J. Hetero. Chem., vol. 21(5): 1533-1535 (1984).
Langis, C., The synthesis of 1,3,4-benzotriazepine-1H-2,5-diones, Chim. Ther., vol. 2: 349-351 (1967).
Peet, N.P., et al., Synthesis of 3,4-dihydro-1H-1,3,4-benzotriazepine, 2,5-diones, J. Org. Chem., vol. 40(13):1909-1914 (1975).
Baronnet, R., et al., Synthesis and pharmacodynamics of 3-dialkylamino-1H, 3H-quinazoline-2,4-diones and derivatives, Eur. J. Med. Chem. —Chim. Ther., vol. 18(3):241-247 (1983).
Davidson, J.S., The preparation of 5-(2-aminophenyl)-1,3,4-oxadiazol-2(3H)-one and its rearrangement to 3-amino-2,4(1H,3H)-quinazolinedione, Moatshefte fur Chem., vol. 115(5):565-572 (1984).
Zhuo, J-C., et al., Boron-containing heterocycles: Syntheses, Structures, and Benzoborauracil Nucleoside, J. Org. Chem., vol. 64(26):9566-9574 (1999).
Database Caplus, Chemical Abstract Service, AN—1998:699954; Bull. Korean Chem. Soc., vol. 19(10):1117-1119 (1998).
Database Caplus, Chemical Abstract Service, AN—1996:275827; J. Hetero. Chem., vol. 33(4):1131-1135 (1996).
Database Caplus, Chemical Abstract Service, AN—1977:468311; J. Org. Chem., vol. 45(15):2551-2556 (1997).
Database Caplus, Chemical Abstrat Service, AN—1968:2872; Helv. Chim. Acta., vol. 50(7):2019-2022 (1968).
Herold, et al., Synthesis and structure of novel 4-arylehexahydro-1H, 3H-pyrido ′1,2-olpyrimidine derivatives, Journal of Heterocyclic Chemistry, Heterocorporation. Provo., US, Vo. 36(2): 389-396 (1999).
Database Crossfile, Beilstein Reg. No. 214132 (1910); Chem. Berich., vol. 43:1236 (1910).
Database Crossfile, Beistein Reg. No. 657750 (1965); Chem. Berich., vol. 98:1505-1510 (1965).
Database Crossfile, Beilstein Reg. No. 169392 (1967); Chem. Ther., vol. 2:1236 (1967).
Database Caplus, Chemical Abstract Service, AN—1997:522336; Arch. Pharm., vol. 330(5): 129-134 (1997).
Database Crossfire Beilstein, Accession No. 8138 (Abstract) Robins, Hitchings: J. Amer. Chem. Soc., vol. 77, p. 2256 (1955).
Database Crossfire Beilstein, Accession No. 157768 (Abstract) Chatterjee, Anand: J. Sci. Ind. Res., vol 17B, p. 63 (1958).
Database Crossfire Beilstein, Accession No. 383776 (Abstract) Jacini: Gazz. Chim. Ital., vol. 73, p. 85 (1943).
Database Crossfire Beilstein, Accession No. 1198342 & 1174334 (Abstract) K. Grohe, H. Heitzer: Justus Liebigs Ann. chem., p. 2066-2073 (1974).
Chemical Abstracts, Abstract No. 233993w, vol. 118:23 (Jun. 7, 1993).
Chemical Abstracts, Abstract No. 339967j, vol. 123:25 (Dec. 18, 1995).
Chemical Abstracts, Abstract No. 17901h, vol. 127:2 (Jul. 14, 1997).
Chemical Abstracts, Abstract No. 34737x, vol. 128:4 (Jan. 26, 1998).
Chemical Abstracts, Abstract No. 237941k, vol. 133:17 (Oct. 23, 2000).

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