Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Parasitic organism or component thereof or substance...
Patent
1978-04-27
1981-03-24
Demers, Arthur P.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Parasitic organism or component thereof or substance...
2602453, 4242484, 424269, 542416, 542434, 542435, 542443, 542444, 542445, 542446, 542436, C07D49804, C07D41306
Patent
active
042580501
ABSTRACT:
Compounds of the formula (II): ##STR1## wherein A is a group such that CO.sub.2 A is carboxylic acid, a non-toxic salt thereof or non-toxic ester thereof; R.sub.1 is COR.sub.4 or OR.sub.5 wherein R.sub.4 is lower alkyl, lower alkenyl, lower alkyl aryl or aryl and R.sub.5 is CO.sub.2 R.sub.6, COR.sub.6 or SO.sub.2 R.sub.6 wherein R.sub.6 is lower alkyl, lower alkenyl, lower alkyl aryl or aryl; and R.sub.2 is COR.sub.8 wherein R.sub.8 is lower alkyl, lower alkenyl, lower alkyl aryl or aryl; when R.sub.1 is COR.sub.4 and R.sub.2 is COR.sub.8, R.sub.4 and R.sub.8 are joined so that the N(COR.sub.4) COR.sub.8 moiety is a 5-,6-, or 7-membered heterocyclic ring or said ring to which is fused a phenyl ring unsubstituted or substituted by one or two lower alkyl, lower alkoxyl, fluorine or chlorine; when R.sub.1 is OR.sub.5 and R.sub.2 is COR.sub.8, R.sub.5 and R.sub.8 are joined so that the N(OR.sub.5) COR.sub.8 moiety is a 5-, 6-, or 7-membered heterocyclic ring, are useful for their antibacterial activity and as synergists for penicillins and cephalosporins.
REFERENCES:
patent: 4078067 (1978-03-01), Christensen et al.
patent: 4079177 (1978-03-01), Harbridge et al.
Beecham Group Limited
Demers Arthur P.
LandOfFree
Antibacterial agents does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Antibacterial agents, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Antibacterial agents will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2408257