Antiatherosclerotic and antithrombotic 2-amino-6-phenyl-4H-pyran

Organic compounds -- part of the class 532-570 series – Organic compounds – Four or more ring nitrogens in the bicyclo ring system

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544124, 544128, 544130, 544141, 544149, 544353, 546207, 546174, 548201, 549419, C07D30938, C07D40504

Patent

active

052527352

ABSTRACT:
This invention relates to compounds of Formula I ##STR1## which are useful as antiatherosclerotic agents and inhibitors of cell proliferation for the treatment of proliferative diseases. In addition, various compounds of Formula I are useful inhibitors of platelet aggregation.

REFERENCES:
patent: 3029256 (1962-04-01), Cook
patent: 3419555 (1968-12-01), Jenkins
patent: 3468915 (1969-09-01), Tate
Capuano, L. et al., "Reactions of 2-Diazo-1,3-diketones with Enamines and Ketene-N,O-Acetals, II," Chem. Ber. 109:3497-3504 (1976).

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