Antiatherosclerotic aminoethenyl furochromones

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C07D31178

Patent

active

045407983

ABSTRACT:
The present invention provides certain novel aminoethanyl furochromones which are useful for antiatherosclerotic purposes.

REFERENCES:
patent: 2680119 (1954-06-01), Robertson et al.
patent: 4284569 (1981-08-01), Gammill
Abu-Shady, H., Experiments with Khellin VII., UAR J. Pharm. Sci., 11:283-288, (1970).
Abu-Shady, H., et al., Experiments with Khellin--VIII., J. Pharm. Belg., 33:397-399, (1978).
Anrep, G. V., et al., Therapeutic Uses of Khellin, The Lancet, pp. 557-558, Apr. 26, 1947.
Anrep, G. V., et al., The Coronary Vasodilator Action of Khellin, Amer. Heart J., 37:531-542, (1949).
Apffel, C. A., Die Zytostatische Wirkung von Chinonen und Ihren Derivaten, Deut. Med. Wochschr., 80:414-416, (1955).
Aubertin, E., La Khelline, Agent de Relachement de la Musculature Lisse, J. Med. Bordeaux, 127:821-823, (1950).
Baytop, O. T., Khellin'in Yer Solucanlarina Tesiri Hakkinda, Folia Pharm., (Turkey), 1:48-49, (1949).
Best, M. M., et al., Effects of Dioxyline Phosphate and Enteric-Coated Khellin on Coronary Artery Insufficiency, Amer. J. Med. Sci., 222:35-39, (1951).
Chen, G., et al., The Central Nervous Depressive Effect of Khellin, Proc. Soc. Expetl. Biol. Med., 78:305-307, (1951).
Colombo, G., et al., Sulla Attivita di Alcune Sostanze del Gruppo Della Kellina Sulla Motilita Ureterale--in vitro--, Arch. Sci. Med., 97:71-81, (1954).
Day, C. E., et al., Utility of a Selected Line (SEA) of the Japanese Quail for the Discovery of New Anti-Atherosclerosis Drugs, Laboratory Animal Science, 27:817-821, (1977).
Eaton, R. P., High Density Lipoprotein--Key to Anti-Atherogenesis, J. Chron. Dis., 31:131-135, (1978).
Haust, M. D., Reaction Patterns of Intimal Mesenchyme to Injury, and Repair in Atherosclerosis, Adv. Exp. Med. Biol., 43:35-57, (1974).
Huttrer, C. P., et al., The Chemistry and Physiological Action of Khellin and Related Products, Chem. Revs., 48:543-579, (1951).
Jordan, H., Cardiovasculare Wirkungen Intravenoser Khellin-Injektionen, Arzneimittel-Forsch, 7:82-85, (1957).
LaBarre, J., et al., A Propos de l'Action Inhibitrice de la Khelline dans l'Ulcere Gastrique Experimental Provoque par Administration Journaliare de Phenylbutazone, Compt. Rend. Soc. Biol., 150:1806-1807, (1956).
Montorsi, W., et al., Sur l'Activite de Certaines Substances du Groupe de la Khelline, Presse Med., 63:81, (1955).
Musante, C., et al., Furil E. Isossazol-Furo-Cromoni e Derivati, Pharmaco. (Pavie) Ed. Sci., 15:81-94, (1960).
Mustafa, A., et al., Experiments with Furochromones, Synthesis of Ammiol and Khellol, J. Org., Chem., 26:886-890, (1961).
Mustafa, A., Furopyrans and Furopyrones, John Wiley and Sons, Inc., NY, (1967), pp. 102-159, (Chapter III: Furochromones).
Osher, H. L. et al., Khellin in the Treatment of Angina Pectoris, New England J. Med., 224:315-321, (1951).
Raymond-Hamet, M., Compt. Rend., 238:1624-1626, (1954).
Samaan, K., et al., The Response of the Heart to Visammin and to Khellinin, J. Pharm. Pharmacol., 1:538-544, (1949).
Samaan, K., et al., The Existence in Ammi Visnaga of a Cardiac Depressant Principle Visammin and a Cardiac Stimulant Glycoside Khellinin, J. Roy, Egypt Med. Assoc., 33:953-960, (1950).
Schonberg, A., et al., Khellin and Allied Compounds, JACS, 72:1611-1617, (1950).
Schonberg, et al., Furo-Chromones and -Coumarins, XIV., JACS, 77:5439-5440, (1955).
Schurr, P. E., High Volume Screening Procedure for Hypobetalipoproteinemia Activity in Rats, Adv. Exp. Med. Biol. 67: Atherosclerotic Drug Discovery, pp. 215-229, Plenum Press, (1975).
Silber, E. N., The Effect of Khellin on Cardio-Pulmonary Function in Chronic Pulmonary Disease, published in 1951, pp. 1046-1054.
Swayne, V. R., et al., Spermicidal Action of Khellin, Amer. J. Pharm., 125:295-298, (1953).

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Antiatherosclerotic aminoethenyl furochromones does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Antiatherosclerotic aminoethenyl furochromones, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Antiatherosclerotic aminoethenyl furochromones will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-1429680

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.