Antiarrythmic and cardioprotective substituted indenoylguanidine

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Nitrogen containing other than solely as a nitrogen in an...

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514615, 564 74, 564147, 564237, 540605, 544330, 544332, 5483301, 5483315, 5483325, A01N 3302, A01N 3730

Patent

active

057339341

ABSTRACT:
Indenoylguanidines of formula I and formula II, the process for their preparation, their use as medicaments, medicaments containing them, their use as diagnostic agents and medicaments containing them are described. Compounds I are useful for treating cardiac arrhythmias. Further they are useful as cardioprotective agents in mammals, which comprises administering the compound of formula-I or II with the above properties in combination with pharmaceutically accepted carrier to said mammal. ##STR1##

REFERENCES:
patent: 2734904 (1956-02-01), Burtner
patent: 3780027 (1973-12-01), Cragoe, Jr. et al.
patent: 4544670 (1985-10-01), Studt et al.

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