Antiarrhythmic substituted N-(2-piperidylmethyl)benzamides

Details Antiarrhythmic substituted N-(2-piperidylmethyl)benzamides Antiarrhythmic substituted N-(2-piperidylmethyl)benzamides

1988-09-26

1990-08-28

Ford, John M.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514316, 514328, 546233, 546234, 546244, 546189, 546208, C07D21130, C07D40100

Patent

active

049525743

ABSTRACT:
Certain 2,5-disubstituted N-(2-piperidylmethyl)benzamides, wherein one substituent is 2,2,2-trifluoroethyoxy, and pharmaceutically acceptable acid-addition salts thereof, are active as antiarrhythmic agents.

REFERENCES:
patent: 3342826 (1967-09-01), Miller et al.
patent: 3900481 (1975-08-01), Banitt et al.
patent: 4071524 (1978-01-01), Banitt
patent: 4097481 (1978-06-01), Banitt et al.
patent: 4339587 (1982-07-01), Banitt
patent: 4452983 (1984-06-01), Johnson et al.
patent: 4558573 (1985-11-01), Bronn
patent: 4599434 (1986-07-01), Banitt
patent: 4650873 (1987-03-01), Leir
patent: 4656285 (1987-04-01), Bronn
J. Med. Chem. 1977, 20, 821 (Banitt, et al.).

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