Antiarrhythmic compounds and pharmaceutical compositions and met

Details Antiarrhythmic compounds and pharmaceutical compositions and met Antiarrhythmic compounds and pharmaceutical compositions and met

1991-01-18

1992-10-13

Brust, Joseph Paul

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Ester doai

558413, 558422, A61K 31275, C07C25550

Patent

active

051551330

ABSTRACT:
A compound of the formula ##STR1## and when appropriate in the form of a racemic mixture or in the form of a stereoisomeric component and the pharmaceutically acceptable salts thereof, in which formula

REFERENCES:
patent: 4544654 (1985-10-01), Davey et al.
G. Duker, et al., Pharmacology & Toxicology, 1988, 63, 85-90.
O. Arunlakshana, et al., Brit. J. Pharmacol. (1959), 14, 48.
Jan E. Alenborg, Computer Methods and Programs in Biomedicine, 28 (1989) 75-85.
Jen T. Weng, M.D., et al., Antiarrhythmic Drugs: Electrophysiological Basis of Their Clinical Use, Am. Thorac. Surg. 1986, 41, 106-112, Williams Foye, Principles of Medicinal Chemistry, 2nd Ed. (1981) pp. 384-385.
Edward Carmeliet, J. Mol. Cell. Cardiol., 23 (Supplement V) (1991) S.79.
Supplement to Circulation, vol. 80 No. 4, Oct. 1989, Abst. No. 2411, 2412.

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