Antiarrhythmic agents

Details Antiarrhythmic agents Antiarrhythmic agents

1985-06-03

1987-01-20

Waddell, Frederick E.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514821, A61K 3140

Patent

active

046380086

ABSTRACT:
This invention provides a group of antiarrythmic agents of the formula: ##STR1## in which R.sub.1 is --CO.sub.2 H, --CO.sub.2 (CH.sub.2).sub.n --NR.sub.4 R.sub.5, --CONR.sub.6 R.sub.7, --NHCO.sub.2 R.sub.8 or --NHCO.sub.2 (CH.sub.2).sub.o --NR.sub.9 R.sub.10 where R.sub.4 and R.sub.5 are H or alkyl of 1 to 6 carbon atoms and n is 1 to 6; R.sub.6 and R.sub.7 are H or alkyl of 1 to 6 carbon atoms; R.sub.8 is alkyl of 1 to 6 carbon atoms; and R.sub.9 and R.sub.10 are alkyl of 2 to 6 carbon atoms and o is 1 to 6;

REFERENCES:
patent: 3282942 (1966-11-01), Rice et al.
Rice et al., J. Med. Chem., 7, 313 (1964).
Derwent 36802 T, 1970.
Derwent 22763 T, 1968.
Derwent 10718 W, 1971.

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