Drug – bio-affecting and body treating compositions – Lymphokine
Patent
1989-03-09
1990-05-01
Rose, Shep K.
Drug, bio-affecting and body treating compositions
Lymphokine
424 78, 424435, A61K 920, A61K 3179
Patent
active
049216953
ABSTRACT:
An antianginal composition in the form of a plate is provided for treating ischemic heart disease and is comprised of a biologically soluble and resolvable film and an antianginal coronary vasodilating nitrate. This film is placed buccally on the gum or mouth mucosa for rapid arresting or prevention of angina pectoris attacks.
The antianginal film is in the form of a plate, 0.1 to 1.5 mm thick, consisting of a biologically soluble and resolvable carrier. Preferably, the film is comprised of a homoploymer of acrylamide or vinylpyrrolidone, or a copolymer thereof with acrylate, containing from 99 to 70 percent by weight of acrylamide with vinylpyrrolidone and from 1 to 30 percent by weight of acrylate having a molecular mass from 50,000 to 1,000,000, and the active principle having antianginal action, the components being taken in the following proportions, in percent by weight:
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Babaian Eduard A.
Davydov Anatoly B.
Gerasimova Galina A.
Khromov Gennady L.
Metelitsa Vladimir I.
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