Antianaphylactic and antibronchospastic piperazinyl-(N-substitut

Details Antianaphylactic and antibronchospastic piperazinyl-(N-substitut Antianaphylactic and antibronchospastic piperazinyl-(N-substitut

1986-06-09

1987-06-23

Ramsuer, Robert W.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

514252, 514255, 544 82, 544121, 544357, 544360, 544372, 544374, 544396, A61K 31495, A61K 31535, C07D29514, C07D41312

Patent

active

046753192

ABSTRACT:
Novel piperazine derivatives having the general formula: ##STR1## wherein R is hydrogen or lower alkyl, A is straight or branched chain lower alkyl, and R.sub.1 and R.sub.2 are each hydrogen, amino, alkylamino, dialkylamino, mono- or di(hydroxyalkyl)amino, morpholino, pyrrolidino, piperidino, N-alkylpiperazino, 1,3-dithiolan-2-ylidenamino, or N-alkylureido, with the proviso that at least one of R.sub.1 and R.sub.2 is other than hydrogen, or the isomeric mixtures, individual enantiomers or pharmaceutically acceptable acid addition salts thereof, are therapeutically useful antianaphylactic and antibronchospastic agents.

REFERENCES:
patent: 3244718 (1966-04-01), Biel

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