Antiamyloid phenylsulfonamides: N-cycloalkylcarboxamides...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Nitrogen containing other than solely as a nitrogen in an...

Reexamination Certificate

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C514S406000, C514S438000, C514S445000, C514S522000, C514S530000, C514S538000, C514S542000, C548S371400, C558S413000, C549S068000, C549S077000, C560S012000, C560S013000, C564S089000, C564S090000

Reexamination Certificate

active

07084178

ABSTRACT:
A series of N-cycloalkylcarboxamide derivatives of N-benzyl benzenesulfonamides of Formula I are described.The compounds inhibit β-amyloid peptide (β-AP) production and are useful in the treatment of Alzheimer's Disease and other conditions characterized by aberrant extracellular deposition of β-amyloid. Pharmaceutical compositions and methods of treatment using these compounds are also disclosed.

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