Antiamnesic use of pteridine derivatives

Details Antiamnesic use of pteridine derivatives Antiamnesic use of pteridine derivatives

1990-02-27

1991-09-10

Shah, Mukund J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

544257, C07D 5728, A61K 31505

Patent

active

050474057

ABSTRACT:
Pteridines of general formula (I): ##STR1## in which Y and Z, which can be identical or different, are hydrogen, OH or NH.sub.2, and X.sub.1 and X.sub.2, which can be identical or different, are hydrogen, OH, C.sub.1 -C.sub.4 alkyl, phenyl, hydroxymethyl or carboxyl, for the preparation of pharmaceutical compositions for treating cognitive pathologies characterized by memory and vigilance disturbances, such as senile dementia of Alzheimer type, multiinfarctual dementia, metabolic encephalopathies, Korsakoff's syndrome, and the consequences of the abuse of certain therapies such as anxiolytic and neuroleptic.

REFERENCES:
patent: 3895012 (1975-07-01), Liede et al.
patent: 4183934 (1980-01-01), Paris et al.

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