Antiallergic pharmaceutical composition and use

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Allergen or component thereof

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424269, 424276, 424277, A61K 3141, A61K 3138, A61K 3139, A61K 31385

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active

040911080

ABSTRACT:
Certain tricyclic sulphoxide compounds each of which is substituted in the 1-,2-,3- or 4-position by a carboxyl or (5-tetrazolyl) group and each of which is optionally substituted in the 5-,6-,7- or 8-position by a second carboxyl or (5-tetrazolyl) group or a substituent selected from cyano, halogen, nitro, alkyl, alkoxy, acyl, amino, acylamino, thioalkyl, alkylsulphinyl and alkylsulphonyl, as well as salts, and optionally substituted esters and amides of the carboxyl substituted compounds and alkyl derivatives of the tetrazolyl substituted compounds, are useful for the relief or prophylaxis of allergic conditions.

REFERENCES:
patent: 2985656 (1951-05-01), Weber
patent: 3642997 (1972-02-01), Shen et al.
J.A.C.S., vol. 19, 208-212 (1956).
Chemical Abstracts vol. 66, (1967), 18458c; vol. 75, 20353v, (1971).

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