Antiallergic imidodisulfamides

Details Antiallergic imidodisulfamides Antiallergic imidodisulfamides

1981-01-05

1983-05-24

Daus, Donald G.

Drug, bio-affecting and body treating compositions

Effervescent or pressurized fluid containing

424258, 546139, 546140, 546146, 564 82, A61K 3147, C07D40112

Patent

active

043850472

ABSTRACT:
Imidodisulfamide derivatives useful in the treatment of allergic conditions are prepared by reaction of an appropriately substituted tetrahydroisoquinoline and bis-(chlorosulfonyl)imide in the presence of a non-nucleophilic organic base. Pharmaceutical compositions and methods of alleviating the symptoms of an allergic response are also disclosed.

REFERENCES:
patent: Re24763 (1960-01-01), Neesby
patent: 3062813 (1962-11-01), Scott
patent: 3882148 (1975-05-01), Augstein et al.
patent: 4252818 (1981-02-01), Rokach et al.
patent: 4296129 (1981-10-01), Kadin et al.
Kalaus et al., "Chemical Abstracts", vol. 72, 1970, Col. 100456h.

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