Antiallergic imidodisulfamides

Details Antiallergic imidodisulfamides Antiallergic imidodisulfamides

1981-02-06

1982-09-21

Helfin, Bernard

Drug, bio-affecting and body treating compositions

Effervescent or pressurized fluid containing

Organic pressurized fluid

424321, 564 79, A61K 31135, C07C14372

Patent

active

043506852

ABSTRACT:
Imidodisulfamide derivatives useful in the treatment of allergic conditions are prepared by reaction of an appropriately substituted phenylcycloalkylamine and bis(chlorosulfonyl)imide in the presence of a non-nucleophilic organic base. Pharmaceutical compositions and methods of inhibiting the symptoms of an allergic response are also disclosed.

REFERENCES:
patent: 3147305 (1964-09-01), Lafferty et al.
patent: 3267139 (1966-08-01), Lafferty et al.
patent: 3383414 (1968-05-01), Houlihan
patent: 3860723 (1975-01-01), Baile et al.
patent: 4292305 (1981-09-01), Ali et al.
Chem. Abstracts 69:2166, (1968).
Chem. Abstracts 52:13664a, (1958).
Chem. Abstracts 60:2800h, (1964).
Chem. Abstracts 68:12390u, (1968).
Chem. Abstracts 76:87545x, (1972).
Chem. Abstracts 88:6264c, (1978).
Derwent's FARMDOC #11,875, (1964).

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