Antiallergic imidodisulfamides

Details Antiallergic imidodisulfamides Antiallergic imidodisulfamides

1980-09-26

1982-03-23

Hollrah, Glennon H.

Drug, bio-affecting and body treating compositions

Combustible or chemically reactive to produce a smoke, mist...

424258, 546140, 546143, A61K 3147, C07D40112

Patent

active

043212549

ABSTRACT:
Imidodisulfamide derivatives useful in the treatment of allergic conditions are prepared by reaction of an appropriately substituted tetrahydroisoquinoline and bis(chlorosulfonyl)imide in the presence of a tertiary amine. Pharmaceutical compositions and methods of inhibiting the symptoms of an allergic response are also disclosed.

REFERENCES:
patent: Re24763 (1960-01-01), Neesby
patent: 3882148 (1975-05-01), Lee et al.
patent: 4252818 (1981-02-01), Rokrah et al.
Appleton, et al., "J. Med. Chem.", vol. 20, No. 3, 1977, pp. 371-379.

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