Antiallergic compostion

Drug – bio-affecting and body treating compositions – Immunoglobulin – antiserum – antibody – or antibody fragment,... – Monoclonal antibody or fragment thereof

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Details

4241251, 424805, 424810, 514885, A61K 3800

Patent

active

060903848

ABSTRACT:
Disclosed is an antiallergic composition comprising, as an active ingredient, a peptide which is capable of binding to human IgE, more specifically the high-affinity immunoglobulin E receptor .alpha. chain or a soluble fragment, which is capable of binding to human IgE, or the high-affinity immunoglobulin E receptor .alpha. chain. The composition is clinically useful for blocking allergic responses.

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Nucleic Acids Research, vol. 16, No. 8 (1988), J. Kochan et al., "Isolation of the gene coding for the alpha subunit of the human high affinity IgE receptor" p. 3584.
Nucleic Acids Research, vol. 13, No. 8 (1985), Andrea Riccio et al., "The human urokinase-plasminogen activator gene and its Promoter" p. 2759-2771.
Biosci. Biotech. Biochem., vol. 56, No. 4 (1992), T. Yamaguchi et al., "Production of human antithrombin-III in a serum-free culture of CHO cells" p. 600-604.
M.C. Ray, et al., J. Immunol., 131(3), 1096-1102 (1983).
U. Bland, et al., J. Biol. Chem., 266(4), 2639-2646 (1991).
C. Ra, et al., International Immunology, 5(1), 47-54 (1993).

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