Antiallergic agent

Details Antiallergic agent Antiallergic agent

2001-10-31

2003-05-13

Barts, Samuel (Department: 1623)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

C536S008000, C424S195110, C424S757000, C435S200000, C549S403000

Reexamination Certificate

active

06562793

ABSTRACT:

BACKGROUND OF THE INVENTION
1. Field of the Invention
This invention relates to a flavonoid glycoside exhibiting an excellent antiallergic effect even in a small amount.
2. Description of the Prior Art
Flavonoids are a class of compounds which are widely distributed in the plant kingdom and have been known from long ago. A flavonoid is a modulator for germination and growth of a seed, as well as is believed to absorb ultraviolet rays in sunlight to protect internal tissues. In particular, it is known that a flavonoid protects and strengthen capillary vessels in human body.
SUMMARY OF THE INVENTION
One aspect of the present invention relates to a product comprising a food, drug or cosmetic and a flavonoid glycoside represented by formula I wherein the flavonoid glycoside is present in an antiallergenic effective amount.
Another aspect of the present invention provides a method of inhibiting histamine release by administering to a mammal an antiallergenic effective amount of a flavonoid glycoside represented by formula I.
Yet another aspect of the present invention provides a method of obtaining a flavonoid glycoside represented by formula I by extracting the flavonoid glycoside from a plant in the Cassia genus.


REFERENCES:
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patent: 05170756 (1993-07-01), None
Barnes et al., “Rationale for the use of Genistein-containing soy matrices in chemoprevention trials for breast and prostate cancer.” Journal of Cellular Biochemistry, Suppl. 22, pp. 181-187, 1995.*
Harborne et al. “Plant Polyphenols: Flavonoids in genotypes of Primula Sinensis.” Biochem. J. 78, 298-306, 1961.*
Buttiner et al. “Anticancer agents from Chilean plants, Cassia Obtusa.” Rev. Latinoamer. Quim. 4(1), 8-14, 1973.*
Ishiguro et al. “Antipruritic effect of Flavonol and 1,4-Naphthoquinone derivatives fromImpatiens balsaminaL.” Phytotherapy Research, vol. 11, 343-47, 1997.*
Budzianowski et al. “Microvascular protective activity of Flavonoid Glucuronides fraction fromTulipa gesneriana.” Phytotherapy Research, 13, 166-68 (1999).*
Harborne, J. and Sherratt, H.S.A.,Biochem. J., vol. 78, 1961, pp. 298-306.

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