Anti-viral triaza compounds

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

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A61K 3133

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active

056631618

ABSTRACT:
A method of inhibiting viruses in which a virus is contacted with an antiviral amount of a compound of formula I. Activity is shown against HIV and other viruses. ##STR1## wherein W is a bridge carbon which has a polar or non-polar side group;

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H-J Choi, "Ph.D. Disseration: Synthesis And Properties of Polycyclic Triamines And Application of Ionophores to Ion-Selective Electrodes", State University of New York at Stony Brook, 1989.
E. DeClercq, et al., "Highly Potent and Selective Inhibition of Human Immunodeficiency Virus by the Bicyclam Derivative JM3100", Antimicrobial Agents And Chemotherapy 38(4):668-674 (Apr. 1994).
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R.F. Schinazi, et al. "Insights into HIV Chemotherapy, " Aids Research and Human Retroviruses 8(6(:963-990 1992.

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