Anti-viral compounds, dosage forms and methods

Details Anti-viral compounds, dosage forms and methods Anti-viral compounds, dosage forms and methods

1992-01-28

1993-02-16

Brown, Johnnie R.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

514 48, 514 50, 514 51, 536 265, A61K 3170, C07H 1700

Patent

active

051871637

ABSTRACT:
Novel anti-viral compounds comprise phosphate-linked dimers of anti-viral nucleoside derivatives, or salts or esters of such nucleoside dimers. Pharmaceutical compositions containing the dimers and methods of treatment utilizing the same are disclosed.

REFERENCES:
patent: 3280104 (1966-10-01), Moffatt et al.
patent: 3317512 (1967-05-01), Wechter
patent: 3397268 (1968-08-01), Hunter
patent: 3457253 (1969-07-01), Wechter
patent: 3817982 (1974-06-01), Verheyden et al.
patent: 4594415 (1986-06-01), Robins et al.
patent: 4724232 (1988-02-01), Rideout et al.
patent: 4837311 (1989-06-01), Tam et al.
patent: 4855304 (1989-08-01), Devash
patent: 4981957 (1991-01-01), Lebleu et al.
Kochetkov et al., Organic Chemistry of Nucleic Acids, pp. 64-75 (Plenum Press 1971).
De Clercq, Meth and Find. Exptl. Clin. Pharmacol., 2(5):253-257 (1980).
Yarchoan et al., Lancet, pp. 575-580 (1986).
Bone et al., Chem. Abstracts, 105:221543t (1986).
Baba et al., Biochem Biophys. Res. Comm., 142: 128-134 (1987).
Herdewijn et al., J. Med. Chem., 30:1270-1278 (1987).
Chu et al., Tetrahedron Lett., 29:5349-5452 (1988).
Vince et al., Biochem Biophys. Res. Comm., 156:1046-1053 (1988).
Mansuri et al., J. Med. Chem., 32:461-466 (1989).
Mitsuya et al., Proc. Natl. Acad. Sci. USA, 83:1911-1915 (1986).
Balzarini et al., Biochem. Biophys. Res. Comm., 140:735-742 (1986).
Dahlberg et al., Proc. Natl. Acad. Sci. USA, 84:2469-2473 (1987).

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