Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1999-10-22
2000-09-05
Berch, Mark L.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
5142352, 514322, 514363, 514370, 514388, 544 54, 544 55, 544139, 546139, 548137, 548181, 5483047, 5483061, A61K 314184, A61K 31541, A61K 315377, C07D23530, C07D41704
Patent
active
061143278
ABSTRACT:
The present application provides a series of benzimidazole compounds of formula I: ##STR1## which inhibit the growth of picornaviruses, such as rhinoviruses (bovine and human), enteroviruses such as polioviruses, coxsackieviruses of the A and B groups, or echo virus, cardioviruses such as encephalomyocarditis (EMC), apthoviruses such as foot and mouth disease virus, and flaviviruses such as hepatitis C virus and bovine viral diarrhea virus.
Such compounds are also useful as intermediates for preparing additional benzimidazole antiviral compounds.
REFERENCES:
patent: 4118742 (1978-10-01), Paget et al.
patent: 4338329 (1982-07-01), Paget et al.
patent: 4420479 (1983-12-01), Morwick et al.
patent: 4434288 (1984-02-01), Wikel, II et al.
patent: 4492708 (1985-01-01), Spitzer
patent: 5545653 (1996-08-01), Miller et al.
patent: 5693661 (1997-12-01), Miller et al.
patent: 5821242 (1998-10-01), Colacino et al.
patent: 5891874 (1999-04-01), Colacino et al.
"Fields Virology, Third Ed.", B. N. Fields et al Eds., Lippincott-Raven, Philadelphia, ,p. 613, 614, 934, 935, & 940.
Encyclopedia of Virology, Academic Press, New York, p. 1115.
Dunlap Steven Eugene
Jungheim Louis Nickolaus
Tebbe Mark Joseph
Voy Gilbert Thomas
Werner John Arnold
Berch Mark L.
Eli Lilly and Company
McKenzie Thomas
Musser Arlene K.
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