Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Food or edible as carrier for pharmaceutical
Patent
1996-04-01
1997-09-16
Bawa, Raj
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Food or edible as carrier for pharmaceutical
424440, 424441, 424451, 424464, 424484, 424535, 424 854, 424 941, 4242081, 4242151, 514 2, 514904, 514905, 514867, 514937, 514962, 514 8, A61K 4500
Patent
active
056677979
ABSTRACT:
An anti-diarrheic product comprises a foodstuff and an anti-rotaviral agent such as human defatted fat globule membranes, the human milk macromolecular fraction, skim milk, curd, whey, the milk mucin complex, the 46 Kd app.MW glycoprotein, a polypeptide having an amino acid sequence having the rotavirus binding specificity of the 46 Kd app.MW HMFG glycoprotein or mixtures thereof. An anti-diarrheal kit comprises the anti-rotaviral agent of this invention and instructions for its use, and optionally a foodstuff. A method for inhibiting or countering rotavirus infection in mammalian cells comprises contacting the cells with an anti-rotaviral amount of the agent of this invention. A therapeutic method for inhibiting the onset of or countering rotavirus infection comprises administering to a subject afflicted with or at risk for rotavirus infections such as those occuring, for example, in infants and children (infantile gasteroenteritis) and immunodeficient persons or those who have received a transplant, an anti-rotaviral effective amount of the agent of this invention.
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Newburg David S.
Peterson Jerry A.
Yolken Robert H.
Amzel Viviana
Bawa Raj
Cancer Research Fund of Contra Costa
Senomed, Inc.
The Johns Hopkins University School of Medicine
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