Anti-viral and immuno stimulator polynucleotide duplex and use t

Details Anti-viral and immuno stimulator polynucleotide duplex and use t Anti-viral and immuno stimulator polynucleotide duplex and use t

1992-09-11

2000-06-27

Peselev, Elli

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

514 23, 514 24, A61K 3170

Patent

active

060807261

ABSTRACT:
A method of treating HSV-2 infection which comprises administering to a host subject to said infection an effective amount of a polynucleotide of the formula polyrI.polyr(C.sub.12 U) where n is an integer from 4 to 29. The polynucleotide is advantageously administered intranasally.

REFERENCES:
patent: 3975520 (1976-08-01), Chain et al.
patent: 3980776 (1976-09-01), Ishida et al.
patent: 4024222 (1977-05-01), Ts'o et al.
patent: 4603131 (1986-07-01), Bernstein et al.
Munk et al, Chemical Abstracts, vol. 77 (1972) No. 32470j. "Effect of poly I:C induced interferon on herpes virus hominis infection".
The Merck Index 9th ed., 1976, p. 137 No. 1059; p. 270, No. 2103; and p. 1202 No. 9046.

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