Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1986-06-26
1988-01-26
Friedman, Stanley J.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514259, A61K 31505, A61V 31505
Patent
active
047217146
ABSTRACT:
An anti-vertigo drug which comprises as an active ingredient 6-amino-2-fluoromethyl-3-(o-tolyl)-4(3H)-quinazolinone (Afloqualone) or a pharmaceutically acceptable acid addition salt thereof, which is effective for the prophylaxis and treatment of vertigo and also such various symptoms accompanied with an abnormality in the reflex system of vestibulo-equilibrium sense as desesthesia of motion and position, nystagmus, dysequilibrium, head deviation, nausea, vomiting, sweating, salivation and tachycardia.
REFERENCES:
The Japanese Journal Of Pharmacology, vol. 40, 1986, Supplementum, p. 189P.
Japan J. Pharmacol. 32, 427-438 (1982), (Chem. Abst., 97, 4959s), pp. 427-438.
Chem. Abst. (100)-29,262F-1984.
Chem. Abst (97)-49597S-1982.
Ishida Ryuichi
Kudo Yukitsuka
Friedman Stanley J.
Tanabe Seiyaku Co. Ltd.
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