Drug – bio-affecting and body treating compositions – Immunoglobulin – antiserum – antibody – or antibody fragment,... – Structurally-modified antibody – immunoglobulin – or fragment...
Reexamination Certificate
2006-06-13
2006-06-13
Helms, Larry R. (Department: 1642)
Drug, bio-affecting and body treating compositions
Immunoglobulin, antiserum, antibody, or antibody fragment,...
Structurally-modified antibody, immunoglobulin, or fragment...
C424S156100, C530S387300, C530S388850
Reexamination Certificate
active
07060269
ABSTRACT:
Humanized and variant anti-VEGF antibodies and various uses therefor are disclosed. The anti-VEGF antibodies have strong binding affinities for VEGF; inhibit VEGF-induced proliferation of endothelial cells in vitro; and inhibit tumor growth in vivo.
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Baca Manuel
Chen Yvonne Man-yee
Lowman Henry B.
Presta Leonard G.
Wells James A.
Cui Steven X.
Genentech Inc.
Genentech, Inc.
Helms Larry R.
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