Anti-ulcerous tyrosine derivatives

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Recombinant or stably-transformed bacterium encoding one or...

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260509, 260557R, 260558A, 260558D, 260558P, 260559R, 260559A, 424320, 560 19, A61K 31085, A61K 31165, C07C10378

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active

040976084

ABSTRACT:
Compounds having the formula ##STR1## wherein R.sub.1 is phenyl or cycloalkyl and the phenyl may have at least one substituent selected from the group consisting of lower alkyl, lower alkoxy, amino and nitro; R.sub.2 is hydrogen or lower alkyl; A is --CH.sub.2 O-- or --CH.sub.2 CH(O-lower alkyl)-; n is zero (0) or one (1); when R.sub.1 together with (A).sub.n is unsubstituted phenyl, R.sub.2 is lower alkyl; and R.sub.3 is hydrogen or lower alkoxy, have anti-ulcerous action.

REFERENCES:
patent: 3103516 (1963-09-01), Schmitt et al.
patent: 3340298 (1967-09-01), Wismeyr et al.
patent: 3846476 (1974-11-01), Kaiser et al.
Miki et al., CA 85:78364w (1976).

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