Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Recombinant or stably-transformed bacterium encoding one or...
Patent
1982-03-22
1984-03-06
Chan, Nicky
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Recombinant or stably-transformed bacterium encoding one or...
424333, 424343, A61K 3120, A61K 3111, A61K 31045
Patent
active
044354231
ABSTRACT:
A process for the preparation of a two-functional-group-containing terpenoid having the general formula: ##STR1## in which n is an integer of from 1 to 5, R represents a hydroxymethyl, formyl or carboxyl group, and A represents the hydrogen atom, or a 2-tetrahydropyranyl, benzyl, methoxymethol or methoxyethoxymethyl group comprising the oxidation with a microorganism belonging to the genus Nocardia. Some of the terpenoids are of value as anti-ulcer agents, while others are useful as intermediates.
REFERENCES:
patent: 4175139 (1979-11-01), Kijima et al.
Kjosen et al., Acta Chem. Scand., 26, 4121 (1972).
Sakagami et al., Agric. Biol. Chem., 43, 2643 (1979).
Mori et al., Tetrahedron, vol. 30, 715 (1974).
Quijano et al., Chem. Lett., 1979, pp. 1387-1388.
Derwent 75049A/42 (9/8/78).
Abe Shinya
Kijima Shizumasa
Kuwana Noriaki
Nakajima Kenji
Sato Akio
Chan Nicky
Eisai Co. Ltd.
General Director of the Agency of Industrial Science and Technol
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