Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1990-08-23
1991-05-21
Lee, Mary C.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514444, 549 58, 549 60, A61K 3134, C07D33356, C07D40902
Patent
active
050176013
ABSTRACT:
A compound of the formula: ##STR1## in which R is alkyl, phenyl or halophenyl; R.sup.2 is substituted phenyl having from 1 to 3 substituents selected from halo, alkyl, alkythio, alkylsulfonyl, cyano, trifluoromethyl, or R.sup.2 is pyridinyl, pyrazinyl, quinolinyl, N-alkylpyrrolyl, thienyl, benzothienyl, or furyl; and n is 1 or 2, are cytoprotective anti-ulcer agents.
REFERENCES:
Tsuge et al., Chem. Letters 323 (1987).
Takashi et al., Chem. Abstracts, vol. 108, No. 13; 112103r (1988).
Tsuge et al., Chem. Abstracts, vol. 107, No. 19, 175802t (1987).
Ito et al., Chem. Abstracts, vol. 96, No. 17, 142535j (1982).
Felman Steven W.
Jirkovsky Ivo L.
Memoli Kevin A.
American Home Products Corporation
Jackson Richard K.
Lee Mary C.
Richter J.
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