Anti-tumour product of bacterial origin

Details Anti-tumour product of bacterial origin Anti-tumour product of bacterial origin

1974-04-29

1976-02-03

Monacell, A. Louis

Textiles: fiber preparation

195100, C12K 300, C12K 110

Patent

active

039363546

ABSTRACT:
Wild strain Lechien of the organism Clostridium perfringens is attenuated with nitrosoguanidine. To produce an anti-tumor preparation, the attenuated organism is grown first on a growth medium then on a sporulation medium and the resulting growth recovered as a bacillary suspension, a spore suspension, or culture filtrates. The preparation in any of these forms has the property of inhibiting the growth of Ehrlich's solid tumor, of reducing the tumor size, and lengthening the survival time of the host.

REFERENCES:
patent: 2787576 (1957-04-01), Kakavas et al.

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