Drug – bio-affecting and body treating compositions – Lymphokine
Patent
1988-05-24
1990-06-05
Moskowitz, Margaret
Drug, bio-affecting and body treating compositions
Lymphokine
424 90, 424 89, 424 93, 514 2, 514 8, 514 21, 530350, 530395, 530403, 530427, 530806, 530828, 530406, 4352401, 4352402, C07K 302, C07K 308, C07K 328, A61K 3900
Patent
active
049312758
ABSTRACT:
There are provided anti-tumor vaccines which contain as active ingredient tumor cells which have been pressure treated so as to augment their antigenic properties, tumor cells treated with cholesteryl hemisuccinate (CHS) and subsequently pressure treated, or plasma membranes from either of, or membrane proteins shed from either of these cells, or a combination of any of these. According to another embodiment, tumor cells are treated with cholesteryl hemisuccinate or by the application and release of pressure, and subsequently with a cross-linking agent. Such cells, plasma membranes obtained from these and proteins shed from the surface of these are effective active ingredients in anti-tumor vaccines.
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Cohen Irun R.
Shinitzky Meir
Kushan Jeff
Moskowitz Margaret
Yeda Research & Development Co. Ltd.
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