Anti-tumor substance

Details Anti-tumor substance Anti-tumor substance

1980-02-21

1982-07-13

Moyer, Donald B.

Drug, bio-affecting and body treating compositions

Fermentate of unknown chemical structure

424123, 424180, 424195, 435101, 536 11, A61K 3500, A61K 3170, C07G 300, C12P 1904

Patent

active

043394353

ABSTRACT:
A piece of internal tissue of the sclerotium of Poria cocos (Fr.) Wolf is transplanted into an artificial culture medium to subject it to pure culture of hyphae of said microorganism, thereby obtaining mycelia, and the thus obtained mycelia are extracted with at least one medium selected from the group consisting of water and water-soluble organic media. The resultant substance has an excellent ani-tumor activity and is low in toxicity.

REFERENCES:
patent: 3987166 (1976-10-01), Komatsu et al.
patent: 4138479 (1979-02-01), Truscheit et al.
Saito et al., Agr. Biol. Chem., vol. 32, No. 10, pp. 1261-1269, (1968).

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