Anti-tumor quinazoline compounds

Details Anti-tumor quinazoline compounds Anti-tumor quinazoline compounds

1981-03-06

1982-08-10

Daus, Donald G.

Organic compounds -- part of the class 532-570 series

Organic compounds

Nitrogen attached directly or indirectly to the purine ring...

424251, 544313, 544287, 548309, C07D40512, A61K 31505, C07D40514

Patent

active

043439403

ABSTRACT:
4-Ethyl-6-methoxy-7-(oxiranylmethoxy)quinazoline and its isomer 4-ethyl-7-methoxy-6-(oxiranylmethoxy)quinazoline have potent anti-tumor activity in animals.

REFERENCES:
patent: 3298291 (1966-04-01), Minielli et al.
patent: 3455920 (1969-07-01), Yale
patent: 3637693 (1972-01-01), Otterstedt et al.
Derwent No. 29,765, South African 67/3220, 9/29/67 (2/1).
Derwent No. 46879w/28, Japan 5-0030-890 23, 3/27/75 (2/4).
Bradner, Cancer and Chemotherapy, vol. 1, 1980, pp. 221-227 (4/11).
Taylor, et al., "Chemical Abstracts", vol. 80, 1974, col. 47718g.

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