Anti-tumor protease preparations

Drug – bio-affecting and body treating compositions – Enzyme or coenzyme containing – Stabilized enzymes or enzymes complexed with nonenzyme

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424 9463, 435220, 435221, A61K 3754, C12N 952, C12N 954

Patent

active

048448974

ABSTRACT:
Method of treating a tumor in a mammal comprises administering to said mammal an effective anti-tumor amount of proteases originating from microorganisms.
Method of treating a tumor in a mammal comprises administering to said mammal an effective anti-tumor amount of a protease originating from a microorganism which protease is chemically modified by one of the following procedures:

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H. Maeda, et al., Protein Tailoring for Food and Medical Uses, pp. 353-382 (edited by R. E. Feeney & J. R. Whitaker), N.Y. (1986).

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