Anti-tumor platinum (IV) complex

Details Anti-tumor platinum (IV) complex Anti-tumor platinum (IV) complex

1994-10-04

1997-07-15

Nazario-Gonzalez, Porfirio

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heavy metal containing doai

556137, A61K 3128, C07F 1500

Patent

active

056483848

ABSTRACT:
Disclosed is an anti-tumor liposoluble platinum (IV) complexes having Formula I, a Formula VI or a Formula XII. Because these complexes have liposoluble groups, they are effective for various internal organ tumors or cancers. ##STR1##

REFERENCES:
patent: 4599352 (1986-07-01), Narayanan et al.
patent: 5288887 (1994-02-01), Khokhar et al.
Siddik et al., Anti-Cancer Drug Design, vol. 9, No. 2, pp. 139-151, (Apr. 1994).
Siddik et al., J. Cancer Res. Clin. Oncol., vol. 120, No. 7, pp. 404-414, (May 1994).
Austin et al., Inorg. Chem., vol. 31, pp. 4281-4285 (1992).
Khokar et al., J. Inorg. Biochem., vol. 50, NO. 2, pp. 79-87 (May 1993).

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