Anti-tumor platinum complexes

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heavy metal containing doai

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556137, A61K 3128, C07F 1500

Patent

active

055479820

ABSTRACT:
Platinum complexes, having anti-tumor activity, which include at least one functional ketone group or aldehyde, optionally conjugated as a linkable hydrazone complex. The functional ketone and aldehyde groups and the functionalized hydrazone complexes are linkable to antibodies, proteins, peptides and compounds having free amine, hydrazine or hydrazide functionality. Such agents are useful as targeted site-specific or disease specific chemotherapeutic agents.

REFERENCES:
patent: 4882447 (1989-11-01), Tsujihara et al.

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