Drug – bio-affecting and body treating compositions – Plant material or plant extract of undetermined constitution... – Containing or obtained from leguminosae
Reexamination Certificate
2002-11-21
2004-10-12
Prout, Rebecca E. (Department: 1652)
Drug, bio-affecting and body treating compositions
Plant material or plant extract of undetermined constitution...
Containing or obtained from leguminosae
C424S499000, C424S776000, C530S370000, C530S379000, C530S389700, C530S391500
Reexamination Certificate
active
06803059
ABSTRACT:
BACKGROUND OF THE INVENTION
There are many ways for treating cancer. Besides the surgery to remove malignant tumor for treating cancer, a chemotherapy or radiation therapy may be applied for the treatment of cancer. However, it will incur side effects to hurt the patient.
It is known that many compositions are derived from Chinese herbal medicines, medicinal plants and extracts thereof for treating cancers. Nevertheless, a single plant extract without being conjugated with other effective ingredients, its anti-tumor effect is still unsatisfactory.
The present inventor has found these phenomena and invented the present anti-tumor composition by conjugating
Canavalia ensiformis
-extracted protein with metal ions.
SUMMARY OF THE INVENTION
The object of the present invention is to provide an anti-tumor pharmaceutical composition comprising the conjugation of
Canavalia ensiformis
-extracted protein with metal ions to form a metalloprotein complex for inhibiting the growth of tumor with enhanced activity and stability, but without toxicity.
REFERENCES:
Pan J. et al. Inhibition of Cell Growth Caused by Aluminum Toxicity Rsults from Auminum-Iduced Cell Death in Breley Supension Cells, J. Plant Nutrition, 2002.*
El-Rahman S. Neuropathology of aluminum toxicity in rats (glutamate and GABA impairment), Pharmacological Reserch, 2003, 47, 189-194.*
Obata F. et al. Preparation of Concanavalin A Consisting Solely of Intact Subunits, J. Biochem., 1978, 84, 103-109.*
Obata F. et al. Concanavalin A Binds Various Numbers of Calcium and Manganese Ions, J. Biochem. 1979, 85, 1037-1045.
Lu Jim
Prout Rebecca E.
Walicka Malgorzata A.
LandOfFree
Anti-tumor metallocomplexes of crude extracts from Canavalia... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Anti-tumor metallocomplexes of crude extracts from Canavalia..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Anti-tumor metallocomplexes of crude extracts from Canavalia... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3297858