Anti-tumor derivatives of butanediol and process of preparation

Details Anti-tumor derivatives of butanediol and process of preparation Anti-tumor derivatives of butanediol and process of preparation

1984-12-18

1987-03-03

Trousof, Natalie

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

C07C 69587, C07C 69533

Patent

active

046474129

ABSTRACT:
Provided herein is a butanediol of the formula: ##STR1## wherein R is an alkyl group containing 5-21 carbon atoms or an alkenyl group containing 5-21 carbon atoms and which contains 1-2 unsaturated bonds. The present invention also contemplates a method of preparing such compounds and the use of such compounds as an anti-tumor agent for treating tumors.

REFERENCES:
patent: 3012064 (1961-12-01), Hertling et al.
Spartel et al, Chimie Therapeutique, 4(3), pp. 207-212, (1969).
Baumann et al, J. Lipid Res., 10, pp. 703-709, (1969).
Langen et al, Acta Biol. Med. Germ., 38(7), pp. 965-974, (1979).
Spartel et al, Chemical Abstracts, vol. 71, No. 110174h, (1969).
Langen et al, Chemical Abstracts, vol. 92, No. 461a, (1980).
Baumann et al, Chemical Abstracts, vol. 72, No. 16639n, (1970).
Ukita et al Chemical and Pharmaceutical Bulletin, vol. 9, 1961, pp. 43-46 and 47-53.

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